IIT Mandi team discovers molecule that can be used for treatment of diabetes

Researchers on the Indian Institute of Technology (IIT) Mandi have found a drug molecule that can be used to deal with diabetes.

In a press launch issued on Monday, IIT Mandi mentioned that the molecule, named PK2, is ready to set off the discharge of insulin by the pancreas and can doubtlessly be used as an orally administered drugs for diabetes.

According to the press assertion the main points of the analysis have been printed within the Journal of Biological Chemistry. Dr. Prosenjit Mondal, Associate Professor, School of Basic Sciences, IIT Mandi has authored the paper. Dr Prosenjit Mondal, mentioned “Current drugs such as exenatide and liraglutide used for diabetes, are administered as injections, and they are costly and unstable after administration. We seek to find simpler drugs that are stable, cheap, and effective against both Type 1 and Type 2 diabetes.”

Diabetes is induced resulting from inadequate insulin launch by the pancreas.

Dr. Prosenjit Mondal factors to a different crucial discovering of their work, “Beyond increasing insulin release, PK2 was also able to prevent and even reverse beta cell loss, a cell essential for insulin production, making it effective for both Type 1 and Type 2 diabetes.”

The paper has been co-authored by Subrata Ghosh, School of Basic Sciences, IIT Mandi, together with Dr. Sunil Kumar, ICAR- IASRI, PUSA, New Delhi, Dr. Budheswar Dehury, ICMR RMRC, Bhubaneswar, Dr. Khyati Girdhar, Ms. Shilpa Thakur, Dr.Abhinav Choubey, Dr. Pankaj Gaur, Ms. Surbhi Dogra, Ms. Bidisha Biswas from IIT Mandi, and Dr.Durgesh Kumar Dwivedi (Regional Ayurvedic Research Institute (RARI) Gwalior),

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