The ICMR has invited independent researchers from throughout India to contribute to the scientific knowledge associated to COVID-19 by submitting their modern analysis concepts in recognized precedence areas, stating that there’s scanty knowledge out there associated to the useful facets of the virus, its transmission dynamics, immunological response to pure an infection and vaccines.
In its name for invitations, the apex analysis physique mentioned the coronavirus pandemic has led to main lack of lives and livelihood.
Despite intense efforts of the worldwide scientific group, there may be scanty knowledge associated to the useful facets of the virus, its transmission dynamics, immunological response to pure an infection and vaccines, it mentioned.
” In addition, it is important to understand the drivers of vaccine hesitancy and reduced uptake, clinical spectrum of the disease and its progression. Also there is a need to formulate the clinical management protocols in line with the emerging global evidence,” the Indian Council of Medical Research (ICMR) mentioned.
It had it has initiated analysis on COVID-19 in ‘activity pressure and intramural mode’. These initiatives had been formulated to tackle probably the most urgent analysis questions within the following domains — medical analysis, diagnostics and biomarkers, epidemiology and surveillance and operations analysis, it added.
“ICMR now invitations independent researchers all throughout the nation to contribute to the scientific knowledge associated to COVID-19 by submitting their modern analysis concepts as temporary idea proposals within the following recognized precedence areas,” the apex analysis physique mentioned.
All idea proposals have to be submitted on-line at https://epms.icmr.org.in as a short 3-4 web page idea notice on/earlier than June 30, the ICMR mentioned.
All idea proposals can be screened at ICMR.
If authorized by the screening committee, chosen investigators can be requested to submit full proposals. The full proposals can be completely reviewed by Project Review Committees and resolution can be made accordingly, the apex analysis physique mentioned.
The precedence areas embody epidemiological and surveillance research to assess the influence on growth of variants between those that are vaccinated and unvaccinated people in a restricted geographic space, seroprevalence research to decide susceptibility of people to SARS-CoV-2, in addition to comply with up seroprevalence research at websites lined earlier to measure the influence of vaccination/herd immunity stage, the IMCR mentioned.
It additionally contains surveillance of COVID-19 reinfections in beforehand contaminated people with identical/totally different SARSCoV-2 strains, effectiveness of vaccines in lowering transmission, growing an acceptable mannequin for surveillance of COVID-19 in faculties and schools.
The precedence areas additionally contains learning immune escape of variant SARS-CoV-2 strains in vaccinated people, immunological facet and vaccine efficacy analysis to research immunological response to the COVID-19 vaccines in numerous populations/inhabitants sub-groups within the nation , period of safety supplied by COVID-19 vaccines, and elements affecting it (age, intercourse, comorbid standing, ethnicity, the ICMR mentioned.
It additionally contains research on correlates of immune safety (in vaccinated in addition to naturally contaminated people), evaluation of antibody and antigen-specific responses in SARS-CoV-2 contaminated and naïve people immunised with COVID-19 vaccines, efficacy of COVID-19 vaccines in beforehand contaminated people, and potential scope of single-dose vaccination in such people to enhance immune response, figuring out the necessity and timing of a 3rd COVID-19 vaccine booster dose by measuring antibody titres and their persistence in vaccinees after the second dose of the vaccine and interchangeability of COVID-19 vaccine amongst others.
Besides, precedence areas embody medical analysis to research adjustments in COVID-19 mortality/ severity/ hospitalisation after vaccination, analysis on put up COVID syndrome/Long COVID, and assessing variations between asymptomatic and symptomatic instances, if any, medical trials of repurposed and new medication and research to assess the security of COVID-19 vaccines in pregnant and breastfeeding ladies in programmatic mode.